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Dutasteride Capsule (Each) †
Dutasteride Capsule (Each) †
† commercial product
By helping to shrink the prostate, it can ease urinary symptoms like difficulty starting urination, weak flow, and frequent nighttime trips to the bathroom. It’s also sometimes used in combination with other treatments for better results. While it doesn’t cure the condition, it helps manage symptoms and improve quality of life when taken consistently under a doctor’s supervision.
Dutasteride works by blocking an enzyme called 5-alpha-reductase. The effect takes time, often a few months, before noticeable improvements occur. It doesn’t stop testosterone from working elsewhere in the body but focuses specifically on limiting DHT-related changes in the prostate.
Dutasteride is not suitable for everyone. Men with known hypersensitivity to the medication or its ingredients should avoid it. It’s not prescribed for women or children. People with liver problems should use it cautiously, as liver function affects how the medicine is processed. If you are taking other medications or have underlying health issues, inform your doctor before starting treatment. Regular checkups are recommended to monitor progress and ensure the medicine is working safely.
Some users may experience side effects like decreased libido, trouble maintaining an erection, or ejaculation problems. Others may notice breast tenderness or swelling, dizziness, or headaches. Long-term use has been linked to changes in PSA (prostate-specific antigen) levels, so regular prostate health screenings are essential.
Dutasteride is not for women, especially those who are pregnant or may become pregnant. It can cause birth defects if a pregnant woman is exposed to it, even through skin contact. Men taking dutasteride are advised to handle the capsules carefully and avoid exposing women to the medication. It’s unclear whether it passes into breast milk, but breastfeeding mothers are strongly advised against using or being exposed to it. Discuss safer treatment options with a healthcare provider if you are planning to start a family.
Store this medication at 68°F to 77°F (20°C to 25°C) and away from heat, moisture and light. Keep all medicine out of the reach of children. Throw away any unused medicine after the beyond use date. Do not flush unused medications or pour down a sink or drain.
- Roehrborn C, Siami P, Barkin J, et al. The effects of dutasteride, tamsulosin and combination therapy on lower urinary tract symptoms in men with benign prostatic hyperplasia and prostatic enlargement: 2-year results from the CombAT study. J Uro
- FDA Drug Safety Communication: 5-alpha reductase inhibitors (5-ARIs) may increase the risk of a more serious form of prostate cancer. Retrieved June 9, 2011. Available on the World Wide Web at: http://www.fda.gov/Drugs/DrugSafety/ucm258314.htm– LinkOpens in New Tab
- McVary KT, Roehrborn CG, Avins AL, et al. American Urological Association guideline: management of benign prostatic hyperplasia (BPH). Linthicum, MD: American Urological Association; 2010. 1-62; Appendix 278-85. Retrieved on February 4, 2020. Available on the Worldwide Web at https://www.auanet.org/guidelines/benign-prostatic-hyperplasia-(bph)-guideline/benign-prostatic-hyperplasia-(2010-reviewed-and-validity-confirmed-2014).– LinkOpens in New Tab
- Dimitropoulos K, Gravas S. Fixed-dose combination therapy with dutasteride and tamsulosin in the management of benign prostatic hyperplasia. Ther Adv Urol 2016;8:19-28.
- Harcha WG, Martinez JB, Tsai TF, et al. A randomized, active- and placebo-controlled study of the efficacy and safety of different doses of dutasteride versus placebo and finasteride in the treatment of male subjects with androgenetic alopecia. J Am Acad Dermatol 2014;70:489-98.
- Avodart (dutasteride soft gelatin capsules) package insert. Research Triangle Park, NC: GlaxoSmithKline; 2020 Jan.
- Amory JK, Wang C, Swerdloff RS, et al. The effect of 5-alpha-reductaxe inhibition with dutasteride and finasteride on semen parameters and serum hormones in healthy men. J Clin Endocrin Metab 2007;92(5):1659-65

