Estriol vaginal cream is a hormone cream that may help to alleviate symptoms of vaginal atrophy associated with menopause, such as dryness, itching, burning and painful intercourse. The cream contains estriol, a weaker form of estrogen, which may help restore estrogen levels in the vaginal tissues.^[1][2]
The cream may be applied intravaginally using an applicator to allow for precise dosing as prescribed by a healthcare provider. Estriol vaginal cream may be an option for women who are not candidates for systemic hormones. This treatment may be an option for women who experience predominantly vaginal symptoms of estrogen deficiency.^[2][3]

Store this medication at 68°F to 77°F (20°C to 25°C) and away from heat, moisture and light. Keep all medicine out of the reach of children. Throw away any unused medicine after the beyond use date. Do not flush unused medications or pour down a sink or drain.

1. National Center for Biotechnology Information. “Estriol.” PubChem, pubchem.ncbi.nlm.nih.gov/compound/Estriol
2. National Center for Biotechnology Information (NCBI). Menopause. In StatPearls. StatPearls Publishing. Retrieved from https://www.ncbi.nlm.nih.gov/books/NBK507826– LinkOpens in New Tab
3. MedlinePlus. Estrogen Vaginal. MedlinePlus. https://medlineplus.gov/druginfo/meds/a606005.html