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GHK-Cu Scalp Solution (60 mL)
GHK-Cu Scalp Solution is a topical treatment designed to promote hair growth, scalp health, and follicle regeneration This solution is commonly used by individuals experiencing hair thinning, shedding, or early-stage hair loss.
GHK-Cu works on the scalp and hair follicles through several well-documented biological actions:
Stimulates Hair Growth
⦁ GHK-Cu increases the expression of genes associated with hair growth and follicle health.
⦁ Encourages the transition of follicles from the resting phase (telogen) to the active growth phase (anagen)
Promotes Angiogenesis
⦁ Enhances blood flow to the scalp by supporting the formation of new capillaries, delivering oxygen and nutrients to hair follicles.
Anti-Inflammatory Effects
⦁ Reduces inflammation in the scalp, which is often associated with hair loss conditions like alopecia and folliculitis.
Antioxidant Protection
⦁ Neutralizes free radicals that contribute to oxidative stress and follicular aging.
Boosts Collagen & ECM (Extracellular Matrix)
⦁ Encourages production of collagen and glycosaminoglycans around the hair follicles, improving scalp structure and follicle anchoring.
Contraindications:
⦁ Known allergy to copper peptides or any ingredients in the formulation.
⦁ Damaged or infected scalp: Avoid use on open wounds, inflamed skin, or active infections.
Precautions:
⦁ Sensitive Skin: Patch test recommended before full use to check for irritation.
⦁ Concurrent Topical Treatments: Be cautious when using with other active ingredients (like minoxidil, retinoids, or steroids), as it may increase irritation.
⦁ Consistency: Results may take weeks to months; regular application is key.
GHK-Cu Scalp Solution has minimal systemic absorption, so drug interactions are rare. However:
⦁ Other Hair Growth Agents (e.g., Minoxidil):
⦁ May be used together, but not simultaneously. Apply at different times (e.g., GHK-Cu in the morning, minoxidil at night) to avoid ingredient interference.
Exfoliating or Irritating Products:
⦁ Using products with strong acids (AHAs/BHAs) or alcohol-based formulations on the scalp may increase sensitivity or reduce GHK-Cu effectiveness.
Metal Ions and Chelators:
⦁ Avoid use with products that contain strong metal chelators (like EDTA), as they may bind copper and reduce activity.
Mild and Common:
⦁ Itching or tingling at application site
⦁ Mild redness or irritation
⦁ Dryness or flakiness on the scalp
Less Common:
⦁ Temporary increase in hair shedding (shedding phase before regrowth)
⦁ Sensitivity when used with other actives
⦁ Contact dermatitis (rare)
Rare but Possible:
⦁ Allergic reaction (rash, swelling, burning sensation)
⦁ If any severe reactions occur, discontinue use and consult a medical professional.
Pregnancy: There is limited safety data on topical GHK-Cu use during pregnancy. While it is a naturally occurring peptide in the body, its effects on a developing fetus are unknown.
Breastfeeding: Since systemic absorption is minimal, topical use on the scalp is unlikely to affect breast milk, but caution is advised. Avoid applying near the breast area
Store this medication in its original container at 68°F to 77°F (20°C to 25°C) and away from heat, moisture and light. Keep all medicine out of the reach of children. Throw away any unused medicine after the beyond use date. Do not flush unused medications or pour down a sink or drain.
- Pickart L, Margolina A. Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data. Int J Mol Sci. 2018 Jul 7;19(7):1987. doi: 10.3390/ijms19071987.
- Liu T, Liu Y, Zhao X, Zhang L, Wang W, Bai D, Liao Y, Wang Z, Wang M, Zhang J. Thermodynamically stable ionic liquid microemulsions pioneer pathways for topical delivery and peptide application. Bioact Mater. 2023 Nov 1;32:502-513. doi: 10.1016/j.bioactmat.2023.10.002.
- Copper Peptides in Skincare. Healthline. Available at: https://www.healthline.com/health/copper-peptides#drawbacks.– LinkOpens in New Tab
- Li H, Toh PZ, Tan JY, Zin MT, Lee CY, Li B, Leolukman M, Bao H, Kang L. Selected Biomarkers Revealed Potential Skin Toxicity Caused by Certain Copper Compounds. Sci Rep. 2016 Nov 28;6:37664. doi: 10.1038/srep37664.
