Part of the Bcomplex family of vitamins known as cobalamins, cyanocobalamin is a synthetic version of vitamin B12. Given its stability, it is frequently included in fortified foods and dietary supplements. Approved by the FDA in 1942, it comes as OTC as well as prescription drugs. Made by microbial fermentation, this vitamin is simpler to crystallize and store than other forms.

✅ Mechanisms of Action

Cyanocobalamin contains a small amount of cobalt at the center of its structure, where it binds to a cyano (cyanide) group. This makes the molecule more stable and less prone to breakdown. Though it’s less biologically active than other forms like hydroxocobalamin, it serves as a source of vitamin B12 in the body. The molecule’s structure helps maintain its effectiveness during storage and manufacturing.

✅ Contraindications & Precautions

Cyanocobalamin should be used cautiously in individuals with hypersensitivity to the compound or its components. It does not occur naturally in foods because it contains cyanide, which is absent in natural B12 forms. The vitamin should be stored carefully because its coenzymes are unstable when exposed to light. It’s essential to keep the compound dry since the anhydrous form can absorb up to 12% moisture from the air.

✅ Adverse Reactions / Side Effects

Some individuals may experience side effects if exposed to improper handling or storage conditions. Light exposure may degrade its activity. Care should be taken to ensure proper administration through tablets, nasal sprays, or injections.

✅ Pregnancy & Breastfeeding

There is no specific information provided regarding the risks of cyanocobalamin during pregnancy or breastfeeding. However, because it is a synthetic form containing cyanide, medical guidance is recommended before use during pregnancy or nursing.

Store this medication at 68°F to 77°F (20°C to 25°C) and away from heat, moisture and light. Keep all medicine out of the reach of children. Throw away any unused medicine after the beyond use date. Do not flush unused medications or pour down a sink or drain.

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